Map Kinase Inhibitor Analogues Compounds and Quinoxalinone Derivatives

نویسندگان

  • KUO CHU HWANG
  • PERIYASAMY MURUGAN
چکیده

This paper reports the synthesis of nitrogen containing heterocyclic compounds such as quinoxalines (5-7), imidazoles (8, 9,10,11), aminothiazole (12), aminooxazole (13), aminoimidazole (14) and benzothiazine (17) from the reaction with unsymmetrical diketone 4, 3 and 4a respectively. The aforementioned compounds with 4-pyridyl,4fluorophenyl groups have different positions in their ring skeleton. The quinoxalinone derivatives (19, 20) were synthesized by the reaction of (18) with o-phenylenediamine and 4,5-dimethylo-phenylenediamine respectively.

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تاریخ انتشار 2014